The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
Category
Antibodies
Product Group
Recombinant Antibodies
Application
ICC, IF, IHC-P, WB
Host
Rabbit
Species reactivity
Cat, Dog, Human, Non-human Primate
Conjugate
Unconjugated
Clone ID
HL1092
Formulation
PBS, no preservative.
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human ACE2. The exact sequence is proprietary.
