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Afatinib

Article
Afatinib
Product Number
S1011-1G
Supplier
Selleck Chemicals
Size
1 g
Description
Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.
Category
Proteins, Peptides and Small Molecules
Product Group
Inhibitors & Activators
CAS Number
850140-72-6
Formulation
C24H25ClFN5O3
Shipping Temperature
BLUE ICE
Supplier URL
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