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Animal-Free Recombinant Human/...

Article
Animal-Free Recombinant Human/Murine/Rat BDNF
Product Number
AF-450-02-2UG
Supplier
Peprotech
Size
2 ug
Description
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human/Murine/Rat BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.
Category
Proteins, Peptides and Small Molecules
Product Group
Growth Factors, Chemokines & Cytokines
Molecular Weight
27 kDa
Synonyms
abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
Unigene ID
627
Gene Symbols
BDNF
Articlegroup
Peprotech Katalog
Shipping Temperature
RT

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