Animal-Free Recombinant Human ...
- Article
- Animal-Free Recombinant Human BDNF
- Product Number
- PC-AF-H-BDNF-500UG
- Supplier
- Pacific Coast Biologics
- Size
- 500 ug
- Description
- BDNF belongs to the NGF family of neurotrophic growth factors, supporting neuron growth and survival. It binds to a low-affinity cell surface receptor, LNGFR, shared with other neurotrophins like NGF, NT-3, and NT-4. However, BDNF primarily exerts its neurotrophic effects through the high-affinity receptor gp145/trkB. Structurally, BDNF is part of a 247 amino acid polypeptide precursor, featuring an 18 amino acid signal sequence and a 110 amino acid propeptide. Recombinant Human/Murine/Rat BDNF exists as a 27.0 kDa homodimer comprising two 120 amino acid subunits held together by robust non-covalent interactions.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Growth Factors, Chemokines & Cytokines
- Purity
- ≥ 98% by SDS-PAGE gel and HPLC analyses
- Molecular Weight
- 27 kDa
- Synonyms
- abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
- Unigene ID
- 627
- Gene Symbols
- BDNF
- Supplier URL
- Visit supplier product page