Animal-Free Recombinant Human ...
- Article
- Animal-Free Recombinant Human Flt3-Ligand
- Product Number
- AF-300-19-100UG
- Supplier
- Peprotech
- Size
- 100 ug
- Description
- Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Growth Factors, Chemokines & Cytokines
- Molecular Weight
- 17.6
- Synonyms
- CD135; CD135 antigen; fetal liver kinase 2; FL cytokine receptor; FLK2; FLK-2; fms related tyrosine kinase 3; fms-like tyrosine kinase 3; growth factor receptor tyrosine kinase type III; receptor-type tyrosine-protein kinase FLT3; stem cell tyrosine kinase 1; STK1; FL; FLG3L; flt3 ligand; FLT3L; fms related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; SL cytokine
- Unigene ID
- 2322
- Gene Symbols
- FLT3
- Articlegroup
- Peprotech Bulk
- Shipping Temperature
- RT