Anti integrin a5b1 [7H5], IgG2...
- Article
- Anti integrin a5b1 [7H5], IgG2a, Fc Silent™
- Product Number
- AB02665-2.3-BT
- Supplier
- Absolute Antibody
- Size
- 1 mg
- Category
- Antibodies
- Product Group
- Recombinant Antibodies
- Application
- ELISA, FC, Func
- Host
- Mouse
- Species reactivity
- Human
- Clone ID
- 7H5
- Formulation
- PBS with 0.02% Proclin 300.
- Immunogen
- The original mouse version of this antibody was raised by immunizing mice with purified human alpha5beta1. Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
- Synonyms
- CD49 antigen-like family member E; CD49e; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; integrin alpha-5; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; very late activation protein 5, alpha subunit; VLA-5; VLA5A
- Unigene ID
- 3678
- Gene Symbols
- ITGA5
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page