A neuroprotective agent, potentiates NGF-induced neurite outgrowth in NS-1 cells (EC50 = ~1 µM), inhibits glutamate-induced excitotoxicity in HT-22 cells in a concentration-dependent manner, inhibits glutamate-induced decreases in GSH levels and increases in Bax levels, intracellular accumulation of calcium, and ROS production in HT-22 cells at 8 µM, inhibits decreases in cell viability, increases in ROS production, and mitochondrial membrane depolarization induced by 6-OHDA in HT-22 cells, an in vitro model of Parkinson's disease
