Bovine CCL4 (MIP-1 beta) ELISA
- Article
- Bovine CCL4 (MIP-1 beta) ELISA
- Product Number
- DIY0660B-003
- Supplier
- Kingfisher Biotech
- Size
- 1 Pack (<= 10 Plates)
- Description
- The Bovine CCL4 (MIP-1 beta) ELISA is a sensitive immunoassay designed for the quantitative detection of bovine CCL4 (macrophage inflammatory protein-1 beta) in cell culture supernatants. With minor protocol adjustments, this ELISA kit can also be used to measure CCL4 in additional biological sample types, offering flexibility for a wide range of immunology, inflammation, and disease research applications. The assay exhibits cross-reactivity with Yak, American Buffalo, and Zebu CCL4, making it an effective tool for comparative immunology and translational studies across related species. Bovine CCL4 (MIP-1 beta) has been successfully detected in multiple sample matrices, including cell culture supernatant, plasma, serum, lymph nodes, gingival tissue, and bronchoalveolar lavage fluid. As a key pro-inflammatory chemokine, MIP-1 beta plays a critical role in immune cell recruitment, particularly T cells and monocytes, and contributes to immune regulation and inflammatory signaling pathways. Quantifying CCL4 levels helps researchers better understand immune responses, inflammatory disease mechanisms, and disease progression. Elevated MIP-1 beta expression has been associated with conditions such as HIV infection, multiple myeloma, multiple sclerosis, and cancer, where it may serve as a biomarker for inflammation severity, bone resorption, and antiviral immune activity. The Bovine CCL4 ELISA kit contains a capture antibody, detection antibody, and a recombinant CCL4 protein standard for assay development. These antibodies have been validated to work together in an ELISA format using the provided standard. Assay conditions-including buffers, antibody concentrations, incubation times, and temperatures-have not been pre-optimized, allowing investigators to tailor assay performance to achieve optimal sensitivity and dynamic range for their specific sample types. Kit component quantities are not matched, and individual reagents are available for purchase separately. This product is for research use only and is manufactured in the USA.
- Category
- Assay Kits
- Product Group
- ELISA Kits
- Application
- ELISA
- Species reactivity
- Bovine, Other Mammal
- Immunogen
- CCL4, MIP-1 beta
- Shipping Temperature
- RT
- Estimated Delivery Time:
- 5 Business Days
- Supplier URL
- Visit supplier product page
