Collagen Type II Antibody
- Article
- Collagen Type II Antibody
- Product Number
- 600-401-104-0.1
- Supplier
- Rockland Immunochemicals
- Size
- 100 ug
- Description
- Rockland produces highly active antibodies and conjugates to collagens. Collagens are highly conserved throughout evolution and are characterized by an uninterrupted ''Glycine-X-Y'' triplet repeat that is a necessary part of the triple helical structure. For these reasons, it is often extremely difficult to generate antibodies with specificities to collagens. The development of 'type' specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. Rockland extensively purifies collagens for immunization from human and bovine placenta and cartilage by limited pepsin digestion and selective salt precipitation. This preparation results in a native conformation of the protein. Antibodies are isolated from rabbit antiserum and are extensively cross-adsorbed by immunoaffinity purification to produce 'type' specific antibodies. Greatly diminished reactivity and selectivity of these antibodies will result if denaturing and reducing conditions are used for SDS-PAGE and immunoblotting. Ideal for investigators involved in Cell Biology, Signal Transduction and Stem Cell research.
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- DB, ELISA, IF, IHC, IP, Multiplex Assay, WB
- Host
- Rabbit
- Species reactivity
- Bovine, Human, Other Mammal
- Conjugate
- Unconjugated
- Formulation
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Immunogen
- Collagen Type II from human knee cartilage and bovine nasal cartilage.
- Synonyms
- alpha-1 type II collagen; ANFH; AOM; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; chondrocalcin; COL11A3; collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen, type II, alpha 1; SEDC; STL1
- Unigene ID
- 1280
- Gene Symbols
- COL2A1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
