E-Cadherin antibody [MSVA-035R...
- Article
- E-Cadherin antibody [MSVA-035R] HistoMAX
- Product Number
- GTX04367-500UL
- Supplier
- GeneTex
- Size
- 500 ul
- Description
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
- Category
- Antibodies
- Product Group
- Monoclonal Antibodies
- Application
- IHC-P
- Host
- Rabbit
- Species reactivity
- Human
- Conjugate
- Unconjugated
- Clone ID
- MSVA-035R
- Formulation
- 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.
- Immunogen
- Recombinant full-length human E-Cadherin protein
- Synonyms
- Arc-1; BCDS1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); cadherin-1; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDHE; cell-CAM 120/80; ECAD; E-cadherin 1; epididymis secretory sperm binding protein; epithelial cadherin; LCAM; UVO; uvomorulin
- Unigene ID
- 999
- Gene Symbols
- CDH1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page