Emetine (hydrochloride hydrate...
- Article
- Emetine (hydrochloride hydrate)
- Product Number
- 21048-50MG
- Supplier
- Cayman Chemical
- Size
- 50 mg
- Description
- An alkaloid with diverse biological activities, active against several strains of E. histolytica amoebae (IC50s = 0.73-10.22 µg/ml), inhibits NF-κB signaling induced by TNF-α or IL-1β (IC50s = 2 and 4.2 µM, respectively, in a cell-based β-lactamase reporter assay), increases caspase-3/7 activity in ME180 cells (EC50 = 1.1 µM), cytotoxic to HeLa cells, reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 0.46 and 0.5 µM, respectively), induces emesis in ferrets at 5 mg/kg, an effect that can be prevented by ondansetron
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Inhibitors & Activators
- CAS Number
- 7083-71-8
- Purity
- ≥85%
- Formulation
- A crystalline solid
- Molecular Weight
- 480.63898|553.6
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
