This secondary conjugate recognizes YOUR rat monoclonal antibody. Fab-ZAP is a chemical conjugate of goat anti-rat monovalent antibody and the ribosome-inactivating protein, saporin. The antibodies used to make FabZAP rat are affinity-purified polyclonal antibodies against both the heavy and light chain of rat IgG. The antibody used in this product will cross-react across immunoglobulin classes and subclasses of the same species as they share the same light chain (either kappa or lambda). This product is routinely tested by cytotoxicity assay.