Flavopiridol (Alvocidib) HCl
- Article
- Flavopiridol (Alvocidib) HCl
- Product Number
- S2679-1G
- Supplier
- Selleck Chemicals
- Size
- 1 g
- Description
- Flavopiridol (Alvocidib) HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2.
- Category
- Lab Reagents & Chemicals
- Product Group
- Biochemicals
- CAS Number
- 131740-09-5
- Formulation
- C21H20ClNO5.HCl
- Shipping Temperature
- BLUE ICE
- Estimated Delivery Time:
- 7
- Supplier URL
- Visit supplier product page
