This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
ELISA, IHC, WB
Host
Rabbit
Species reactivity
Human, Mouse
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen
A portion of amino acids 364-391 from the human protein was used as the immunogen for this GCNT2 antibody.
