This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
IHC, WB
Host
Rabbit
Species reactivity
Human, Porcine
Conjugate
Unconjugated
Formulation
PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human GPR30. The exact sequence is proprietary.
