HLA DP/DQ/DR mAb (IVA12), InVi...
- Article
- HLA DP/DQ/DR mAb (IVA12), InVivoPure+
- Product Number
- AK3601P+-25MG
- Supplier
- InVivo BioTech Services
- Size
- 25 mg
- Description
- The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.
- Category
- Antibodies
- Product Group
- Monoclonal Antibodies
- Application
- Blk
- Host
- Mouse
- Species reactivity
- Human
- Clone ID
- IVA12
- Purity
- ≥ 95 % (CGE, reducing conditions) ≤ 5 % aggregates (analytical SEC) Endotoxin level ≤ 1 EU/mg
- Formulation
- Clear Liquid, PBS, pH 7.4, 0.2 µm sterile filtered
- Immunogen
- Animals were immunized with the Priess human B cell line
- Supplier URL
- Visit supplier product page