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Human/Mouse/Rat Activin A Prot...

Article
Human/Mouse/Rat Activin A Protein, Ultra Low Endotoxin (ACV-HM001-UL)
Product Number
ACV-HM001-UL-500UG
Supplier
Kactus Bio
Size
500 ug
Description
Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.
Category
Proteins, Peptides and Small Molecules
Product Group
Growth Factors, Chemokines & Cytokines
Purity
>95%
Formulation
Lyophilized from 0.22µm filtered solution in 4mM HCI. Normally 8% trehalose is added as protectant before lyophilization.
Molecular Weight
The protein has a predicted MW of 12.97 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 23-30 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Synonyms
activin beta-A chain; EDF; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; inhibin beta A chain; inhibin beta A subunit; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1
Unigene ID
3624
Gene Symbols
INHBA
Shipping Temperature
RT
Supplier URL
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