Animal-Free Recombinant Human/...
- Article
- Animal-Free Recombinant Human/Murine/Rat BDNF
- Product Number
- AF-450-02-50UG
- Supplier
- Peprotech
- Size
- 50 ug
- Description
- BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human/Murine/Rat BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Growth Factors, Chemokines & Cytokines
- Molecular Weight
- 27 kDa
- Synonyms
- abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
- Unigene ID
- 627
- Gene Symbols
- BDNF
- Articlegroup
- Peprotech Bulk
- Shipping Temperature
- RT