Human 2B4/CD244/SLAMF4 Protein...
- Article
- Human 2B4/CD244/SLAMF4 Protein (2B4-HM201)
- Product Number
- 2B4-HM201-500UG
- Supplier
- Kactus Bio
- Size
- 500 ug
- Description
- 2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Purity
- >95%
- Formulation
- Lyophilized from 0.22µm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
- Molecular Weight
- The protein has a predicted MW of 49 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
- Synonyms
- NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; Signaling lymphocytic activation molecule 4; SLAM family member 4
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page
