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Human 2B4 / CD244 / SLAMF4 Pro...

Article
Human 2B4 / CD244 / SLAMF4 Protein, Fc Tag
Product Number
2B4-H5255-100UG
Supplier
Acro Biosystems
Size
100 ug
Description
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
Category
Proteins, Peptides and Small Molecules
Product Group
Proteins
Conjugate
Unconjugated
Formulation
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Molecular Weight
48.9 kDa
Synonyms
NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; SLAM family member 4; Signaling lymphocytic activation molecule 4
Shipping Temperature
RT
Supplier URL
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