Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein-coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Category
Proteins, Peptides and Small Molecules
Product Group
Proteins
Purity
>95%
Formulation
Supplied as 0.22µm filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Molecular Weight
The target protein has a predicted MW of 39.6 kDa.
