Human HLA-A*11:01&B2M&KRAS G12...
- Article
- Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein (MHC-HM421)
- Product Number
- MHC-HM421-500UG
- Supplier
- Kactus Bio
- Size
- 500 ug
- Description
- Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Purity
- >95%
- Formulation
- Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- Molecular Weight
- The protein has a predicted MW of 50.3 kDa. Due to glycosylation, the protein migrates to 51-60 kDa based on Bis-Tris PAGE result.
- Synonyms
- beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin; IMD43
- Unigene ID
- 567
- Gene Symbols
- B2M
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page
