Human R-Spondin 1 / RSPO1 Prot...
- Article
- Human R-Spondin 1 / RSPO1 Protein, His Tag
- Product Number
- RS1-H4221-1MG
- Supplier
- Acro Biosystems
- Size
- 1 mg
- Description
- R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Conjugate
- Unconjugated
- Formulation
- PBS
- Molecular Weight
- 28.7 kDa
- Synonyms
- Roof plate-specific spondin-1
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page
