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IWP-2

Article
IWP-2
Product Number
HY-13912-25MG
Supplier
MedChemExpress
Size
25 mg
Description
IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ[1][2].
Category
Lab Reagents & Chemicals
Product Group
Biochemicals
CAS Number
686770-61-6
Purity
99.93
Molecular Weight
466.60
Shipping Temperature
RT

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