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Indoxyl Sulfate (potassium sal...

Article
Indoxyl Sulfate (potassium salt)
Product Number
16926-100MG
Supplier
Cayman Chemical
Size
100 mg
Description
A uremic toxin and metabolite of tryptophan, activates AhR in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay), inhibits OAT1 and OAT3 (Kis = 34.2 and 74.4 µM, respectively for the rat transporters) in S2 proximal tubule cells, increases superoxide anion and nitric oxide levels in isolated human mononuclear blood cells at 0.2 and 1 mM, increases serum creatinine and BUN levels in the 5/6 nephrectomized rat model of chronic renal failure at 50 mg/kg
Category
Lab Reagents & Chemicals
Product Group
Biochemicals
CAS Number
2642-37-7
Purity
≥98%
Formulation
A crystalline solid
Molecular Weight
212.20358|251.30188
Shipping Temperature
DRY ICE
Supplier URL
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