The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
WB
Host
Rabbit
Species reactivity
Human
Conjugate
Unconjugated
Formulation
PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human JAK3. The exact sequence is proprietary.
