Laduviglusib (CHIR-99021) HCl
- Article
- Laduviglusib (CHIR-99021) HCl
- Product Number
- S2924-1G
- Supplier
- Selleck Chemicals
- Size
- 1 g
- Description
- Laduviglusib (CHIR-99021, CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-catenin signaling pathway. CHIR-99021 significantly rescues light-induced autophagy and augments GR, RORα and autophagy-related proteins.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Inhibitors & Activators
- CAS Number
- 1797989-42-4
- Formulation
- C22H18Cl2N8.HCl
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
