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Laduviglusib (monohydrochlorid...

Article
Laduviglusib (monohydrochloride)
Product Number
HY-10182A-1ML
Supplier
MedChemExpress
Size
1 ml
Description
Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy[1][2][3].
Category
Lab Reagents & Chemicals
Product Group
Biochemicals
CAS Number
1797989-42-4
Purity
99.93
Molecular Weight
501.80
Shipping Temperature
RT

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