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NLK antibody [N3C3]

Article
NLK antibody [N3C3]
Product Number
GTX107910-25UL
Supplier
GeneTex
Size
25 ul
Description
Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity). Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
ICC, IF, IHC-P, WB
Host
Rabbit
Species reactivity
Human, Mouse
Conjugate
Unconjugated
Formulation
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen
Recombinant protein encompassing a sequence within the center region of human NLK. The exact sequence is proprietary.
Synonyms
serine/threonine-protein kinase NLK; Nemo-like kinase; Protein LAK1
Unigene ID
51701
Gene Symbols
NLK
Shipping Temperature
BLUE ICE
Supplier URL
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