Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
FACS, ICC, IF, IHC-Fr, IHC-P, WB
Host
Rabbit
Species reactivity
Human
Conjugate
Unconjugated
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PD-L1. The exact sequence is proprietary.