PI(3)P PIP Beads are composed of agarose with 10 nanomoles of bound PI(3)P per mL of beads, enough for several protein binding experiments. Each 1 mL order of PIP Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase. \n \n \n \nApplications \nPIP BeadsTM are designed for use in protein pull-down experiments to identify and characterize lipid binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis. \nStorage \n4 °C - do not freeze \nFeatured in Publications \n1) Mosesson, Y., D. Chetrit, et al. (2009). "Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling." Dev Cell 16(5): 687-98. \n2) Zhang, P., Y. Wang, et al. (2010). "Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum." Proceedings of the National Academy of Sciences 107(26): 11829-11834. \n3) Galvez-Santisteban, M., Rodriguez-Fraticelli, A. and Martin-Belmonte, F. (2014). Phosphoinositides Coated Beads Binding Assay. Bio-protocol 4(3): e1039. \n \nBeing bio-reactive blog: "Lipid-Ligand interaction tools: lipids are not scary intermediates anymore" \n \n \n \nDocuments \nTechnical Data Sheet
