A diterpenoid with diverse biological activities, increases secreted hydrogen peroxide levels in isolated mouse macrophages at 2 mg/ml, toxic to water fleas and rainbow trout (LC50s = 0.1 and 0.5 mg/L, respectively), phloem levels are increased in mechanically injured, as well as mechanically injured and L. abietinum-infected, red pine and white spruce trees, has been found as an environmental contaminant in pulp and paper mill effluent
