Recombinant Human IGF-BP3
- Article
- Recombinant Human IGF-BP3
- Product Number
- 100-08-100UG
- Supplier
- Peprotech
- Size
- 100 ug
- Description
- IGF-BP3 is a 30 kDa, cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals, and it is also found in alpha-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors, such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant Human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Molecular Weight
- 28.8
- Synonyms
- acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP-53; growth hormone-dependent binding protein; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; insulin-like growth factor-binding protein 3
- Unigene ID
- 3486
- Gene Symbols
- IGFBP3
- Articlegroup
- Peprotech Bulk
- Shipping Temperature
- RT