Il-15 (Interleukin-15), is a member of the Il-2 cytokines family. Il-15 performs biological functions by γ c receptor subunits. Several therapies targeting solid tumor and blood cell tumor have entered the clinic study. Although both IL-2 and IL-15 are involved in early T cell proliferation and activation. The antitumor activity of IL-15 also comes from direct activation of CD8+ effector T cells in a non-specific antigen immunogenicity way. It is reported that there has been clinic study of IL-15 targeting immune cell therapy entering phase I. This product is from a large scale GMP leveled Recombinant Human Il-15 production via E. coli expression. Applying pharmaceutical leveled adjuvants and materials for production, strictly controlling host protein residues, nucleic acid residues, pathogene contamination and other impurities, we guarantee an auditable manufacture and quality control practice complying to GMP regulation, as well as all the materials traceable.
