Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech's E.coli derived murine BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Murine BMP-4 is 23.9 kDa.
Category
Proteins, Peptides and Small Molecules
Product Group
Growth Factors, Chemokines & Cytokines
Molecular Weight
23.9
Synonyms
Bmp-; Bmp2; Bmp2b; Bmp2b-; Bmp2b1; Bmp2b-1; Bmp-4; bone morphogenetic protein 2B; bone morphogenetic protein 4
