Recombinant Murine FGF-23
- Article
- Recombinant Murine FGF-23
- Product Number
- 450-55-100UG
- Supplier
- Peprotech
- Size
- 100 ug
- Description
- The FGF family plays a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant Murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Growth Factors, Chemokines & Cytokines
- Molecular Weight
- 25.5 kDa
- Synonyms
- FGF-23; Fgf8b; fibroblast growth factor 23; fibroblast growth factor 8b
- Unigene ID
- 64654
- Gene Symbols
- Fgf23
- Articlegroup
- Peprotech Bulk
- Shipping Temperature
- RT