CAS Number: 76524-84-0Molecular Weight: 1299.66Salt Form: TFAPurity: >96%Sequence (3-letter): Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMCSequence (1-letter): Suc-RPFHLLVY-AMCStorage: -20 °C or belowRenin Substrate I is a fluorogenic substrate for Renin which controls vasoconstriction and blood pressure as part of the Renin-angiotensin system (RAS). This peptide also acts as a substrate for the chymotrypsin-like activity of the 20S proteasome.Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.References K. Murakami T. Ohsawa S. Hirose K. Takada and S. Sakakibara Anal. Biochem. 110 232 (1981). H. Yokosawa H. Ito S. Murata and S. Ishii Anal. Biochem. 134 210 (1983).
