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SOCS1 antibody

Article
SOCS1 antibody
Product Number
GTX100657-25UL
Supplier
GeneTex
Size
25 ul
Description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
ICC, IF, IHC-P, WB
Host
Rabbit
Species reactivity
Human, Mouse
Conjugate
Unconjugated
Formulation
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOCS1. The exact sequence is proprietary.
Synonyms
AISIMD; CIS1; CISH1; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3; JAK-binding protein
Unigene ID
8651
Gene Symbols
SOCS1
Shipping Temperature
BLUE ICE
Supplier URL
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