This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
ICC, IF, IHC-P, IP, WB
Host
Rabbit
Species reactivity
Human, Mouse, Non-human Primate
Conjugate
Unconjugated
Formulation
PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen
Recombinant protein encompassing a sequence within the center region of human SUV39H1. The exact sequence is proprietary.