An NSAID and a prodrug form of salicylic acid, inhibits PGE2 production in human whole blood stimulated with LPS (IC50 = 39.9 µM), inhibits weight gain and decreases fasting plasma glucose and insulin levels, as well as decreases plasma cholesterol and triglyceride levels in a mouse model of high-fat high-cholesterol diet-induced NASH at 1,000 mg/kg
