Sepantronium Bromide (YM155)
- Article
- Sepantronium Bromide (YM155)
- Product Number
- S1130-1G
- Supplier
- Selleck Chemicals
- Size
- 1 g
- Description
- Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells, does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Inhibitors & Activators
- CAS Number
- 781661-94-7
- Formulation
- C20H19BrN4O3
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
