Stabilin-2 mAb (3.1), InVivoPu...
- Article
- Stabilin-2 mAb (3.1), InVivoPure
- Product Number
- AK2810P-10MG
- Supplier
- InVivo BioTech Services
- Size
- 10 mg
- Description
- Stabilin-2, also known as Feel2, FEX2, FELE-2, FELL2, is a conserved class H scavenger receptors expressed by sinusoidal endothelial cells (ECs) in the liver, lymph nodes, spleen and bone marrow. Stabilin-2 is the major receptor for hyaluronan, blocking antibodies or genetic ablation of Stabilin-2 inhibits hyaluronan uptake and leads to increased systemic hyaluronan levels. Besides hyaluronan, Stabilin-2 also binds other glycosaminoglycans, including heparin. It is also involved in antisense oligonucleotide pharmacokinetics and nanoparticle uptake, and it controls Von Willebrandt factor-factor VIII complex half-life and immunogenicity. The antibody is suitable material for validation and was used in the following applications: IF, IHC staining of rat, mouse spleen or liver, FACS on stably full length mStab2 transfected HEK293 cells and in in-vivo blocking studies.
- Category
- Antibodies
- Product Group
- Monoclonal Antibodies
- Application
- Blk
- Host
- Mouse
- Species reactivity
- Mouse
- Conjugate
- Unconjugated
- Clone ID
- 3.1
- Purity
- >=90%
- Formulation
- Clear Liquid, PBS, pH 7.4, 0.2 µm sterile filtered
- Immunogen
- Recombinant mouse Stabilin-2 fragment (residues 1-330 of Q8R4U0, fused to mouse IgG2b-Fc)
- Synonyms
- Ly101; mPD-1; PD-; PD-1; Pdc; Pdc1; programmed cell death 1 protein; programmed cell death protein 1; protein PD-1
- Unigene ID
- 18566
- Gene Symbols
- Pdcd1
- Supplier URL
- Visit supplier product page