CAS Number: 108334-68-5Molecular Weight: 1506.92Salt Form: AcetatePurity: >96%Sequence (3-letter): Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OHSequence (1-letter): PLARTLSVAGLPGKK-OHStorage: -20 °C or belowSolubility: Soluble in water (1 mg/ml)Syntide 2 is a synthetic peptide recognized as a substrate by Caa²a calmodulin-dependent protein kinase II and Caa²a phospholipid-dependent protein kinase (PKC). The sequence is homologous to phosphorylation site 2 on glycogen synthase. Syntide 2 has been used as a probe to assay localization of CaMKII activity and to study the effects of point mutations on phosphorylation activity.References1. Enslen H. et al. (1994) aoeCharacterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulationa J. Biol. Chem. 269: 15520-15527.2. Yamazaki T. et al. (1996) aoeEndothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophya J. Biol. Chem. 271: 3221-3228.
