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Syntide 2, CaMKII Substrate

Article
Syntide 2, CaMKII Substrate
Product Number
105-77-1MG
Supplier
Echelon Biosciences
Size
1 mg
Description
CAS Number: 108334-68-5 \nMolecular Weight: 1506.92 \nSalt Form: Acetate \nPurity: >96% \nSequence (3-letter): Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH \nSequence (1-letter): PLARTLSVAGLPGKK-OH \nStorage: -20 ?C or below \nSolubility: Soluble in water (1 mg/ml) \n \nSyntide 2 is a synthetic peptide recognized as a substrate by Ca?? calmodulin-dependent protein kinase II and Ca?? phospholipid-dependent protein kinase (PKC). The sequence is homologous to phosphorylation site 2 on glycogen synthase. Syntide 2 has been used as a probe to assay localization of CaMKII activity and to study the effects of point mutations on phosphorylation activity. \nReferences \n1. Enslen, H. et al. (1994) ?Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation? J. Biol. Chem. 269: 15520-15527. \n2. Yamazaki, T. et al. (1996) ?Endothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophy? J. Biol. Chem. 271: 3221-3228.
Category
Proteins, Peptides and Small Molecules
Product Group
Peptides
CAS Number
108334-68-5
Molecular Weight
1506.92
Shipping Temperature
RT
Supplier URL
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