Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
ELISA, WB
Host
Mouse
Species reactivity
Human, Mouse, Rat
Clone ID
384CT24.1.3.4
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen
A portion of amino acids 262-290 from the human protein was used as the immunogen for this TLE4 antibody.
Synonyms
B lymphocyte gene 1; BCE1; BCE-1; E(spI); E(spl); enhancer of split groucho 4; ESG; ESG4; GRG4; Grg-4; groucho-related protein 4; transducin like enhancer of split 4; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, homolog of Drosophila E(sp1); transducin-like enhancer protein 4
