A typical antipsychotic, binds to dopamine D2, histamine H1, M3 muscarinic, and α1- and α2-adrenergic receptors (Kis = 5-341.3 nM), as well as 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 receptors (Kis = 10-180.7 nM), reduces amphetamine-induced repetitive head bobbing and oral behavior in rats at 5 mg/kg, reduces conditioned fear stress-induced freezing behavior in rats from 3 to 100 mg/kg, active against multidrug-resistant tuberculosis in vitro and in vivo
