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Thyroglobulin antibody [MSVA-1...

Article
Thyroglobulin antibody [MSVA-189R] HistoMAX
Product Number
GTX04365-500UL
Supplier
GeneTex
Size
500 ul
Description
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
IHC-P
Host
Rabbit
Species reactivity
Human
Conjugate
Unconjugated
Clone ID
MSVA-189R
Formulation
10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.
Immunogen
Recombinant human Thyroglobulin protein
Synonyms
AITD3; TGN; thyroglobulin
Unigene ID
7038
Gene Symbols
TG
Shipping Temperature
BLUE ICE
Supplier URL
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