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VX-702

Article
VX-702
Product Number
13108-10MG
Supplier
Cayman Chemical
Size
10 mg
Description
A third generation inhibitor of p38 MAP kinases, binding to both p38α and p38β (Kd = 3.7 and 17 nM, respectively), inhibits IL-6, IL-1β, and TNF-α production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml, respectively
Category
Proteins, Peptides and Small Molecules
Product Group
Inhibitors & Activators
CAS Number
745833-23-2
Purity
≥95%
Formulation
A crystalline solid
Molecular Weight
404.3
Shipping Temperature
DRY ICE
Supplier URL
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