Vibrio cholerae serotype O1 (s...
- Article
- Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Cholera enterotoxin subunit B Protein, His Tag (MALS verified)
- Product Number
- GHB-V52H3-500UG
- Supplier
- Acro Biosystems
- Size
- 500 ug
- Description
- Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Natural Compounds
- Conjugate
- Unconjugated
- Formulation
- PBS
- Molecular Weight
- 13.5 kDa
- Synonyms
- cholera enterotoxin binding subunit CtxB; VC_1456; VC_RS07050; VC1456; Cholera enterotoxin B chain; Cholera enterotoxin gamma chain; Choleragenoid
- Unigene ID
- 2613962
- Gene Symbols
- ctxB
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page
