anti TGF beta antibody [TB21]
- Article
- anti TGF beta antibody [TB21]
- Product Number
- ARG10002-100UG
- Supplier
- Arigo Biolaboratories
- Size
- 100 ug
- Description
- This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]
- Category
- Antibodies
- Product Group
- Monoclonal Antibodies
- Application
- ELISA, ICC, IF, IHC-Fr, IHC-P, Neut, WB
- Host
- Mouse
- Species reactivity
- Bovine, Human, Mouse, Other Mammal, Porcine, Rabbit, Rat, Sheep
- Conjugate
- Unconjugated
- Clone ID
- TB21
- Formulation
- 0.01M PBS (pH 7.0)
- Immunogen
- TGF-b from human platelets
- Synonyms
- CED; DPD1; IBDIMDE; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; TGFB; TGFbeta; TGF-beta1; TGF-beta-1; transforming growth factor beta1; transforming growth factor beta-1 proprotein
- Unigene ID
- 7040
- Gene Symbols
- TGFB1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
![Immunohistochemistry: Mouse tibiae stained with ARG10002 anti-TGF beta antibody [TB21] at 1:200 dilution.](http://www.arigobio.com/files/product/3849/10002.jpg)